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Use of clerodendrum sp. for treating tic disorders or psychiatric disorders with sensorimotor gating deficits Download PDF Info Publication number US20110159129A1. US20110159129A1 US12/827,412 US82741210A US2011159129A1 US 20110159129 A1 US20110159129 A1 US 20110159129A1 US 82741210 A US82741210 A US 82741210A US 2011159129 A1 US2011159129 A1 Deficiencies in sensorimotor gating contribute to the manifestation of a number of neuropsychiatric disorders. PPI refers to a reduction of the startle reflex following exposure to a weak-intensity prepulse that is administered immediately prior to a startle stimulus; this is a well-established method used to evaluate sensorimotor gating [4].
2001-09-15 1990-02-01 Impaired Sensorimotor Gating Using the Acoustic Prepulse Inhibition Paradigm in Individuals at a Clinical High Risk for Psychosis Previous studies have shown impaired PPI in several neuropsychiatric disorders, such as schizophrenia, bipolar disorder, obsessive-compulsive disorder, Huntington, Tourette, Sensory input may be abnormal and trigger focal dystonia, or defective “gating” may cause an input–output mismatch in specific motor programs. Altogether, several observations strongly support the idea that sensorimotor integration is impaired in focal dystonia. 2009-06-01 Although elemental sensation is normal in patients with tics, tics can be associated with sensory phenomena. Some neurophysiological studies suggest that an altered “gating” mechanism also underlies the development of tics.
In two distinct auditory paradigms sensory gating, indexed as P50 suppression, and sensorimotor gating, indexed as prepulse inhibition (PPI), startle reactivity, and habituation of the eye-blink startle response were examined. Within the P50 paradigm, N100 and P200 amplitudes were also assessed.
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PURPOSE: Auditory processing is one of the most commonly reported sensory processing impairments in autism spectrum disorders. This study sought to determine whether children with high-functioning autism (HFA) differ from typically developing (TD) children on sensory gating, as measured by the P50 event-related potential (ERP) component. Sensory processing disorder ( SPD; also known as sensory integration dysfunction) is a condition where multisensory integration is not adequately processed in order to provide appropriate responses to the demands of the environment.
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gating distal pseudocoordinations like vara och + V 'be and V', notes that the most sensorimotor control, whereas lying requires least control, sitting being.
Studies of PPI as an operational measure of sensorimotor gating were originally intended to test the general theory that failures of inhibitory filtering mechanisms can lead to sensory overload and consequent cognitive fragmentation in schizophrenia (Geyer and Braff, 1987; Braff and Geyer, 1990).
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Altogether, several observations strongly support the idea that sensorimotor integration is impaired in focal dystonia.
Abstract. Functional gating is an important function of the brain, preventing it from a sensory overload by filtering out irrelevant stimuli. 2001-09-15
1990-02-01
Impaired Sensorimotor Gating Using the Acoustic Prepulse Inhibition Paradigm in Individuals at a Clinical High Risk for Psychosis Previous studies have shown impaired PPI in several neuropsychiatric disorders, such as schizophrenia, bipolar disorder, obsessive-compulsive disorder, Huntington, Tourette,
Sensory input may be abnormal and trigger focal dystonia, or defective “gating” may cause an input–output mismatch in specific motor programs.
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2001-09-15 1990-02-01 Impaired Sensorimotor Gating Using the Acoustic Prepulse Inhibition Paradigm in Individuals at a Clinical High Risk for Psychosis Previous studies have shown impaired PPI in several neuropsychiatric disorders, such as schizophrenia, bipolar disorder, obsessive-compulsive disorder, Huntington, Tourette, Sensory input may be abnormal and trigger focal dystonia, or defective “gating” may cause an input–output mismatch in specific motor programs. Altogether, several observations strongly support the idea that sensorimotor integration is impaired in focal dystonia.
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9. 1 Jun 2009 Abstract. Disrupted sensorimotor gating has been found in various neuropsychiatric conditions which are characterized by impaired attention, Sensorimotor gating was abnormal, as measured by deficits in prepulse inhibition of acoustic and tactile startle.
Altogether, several observations strongly support the idea that sensorimotor integration is impaired in focal dystonia. Reductions in sensorimotor gating are theorized to reflect deficient central inhibitory functioning and underlie symptoms of several neuropsychiatric disorders, including the obsessions and compulsions of OCD (Swerdlow et al, 1993; Hoenig et al, 2005). Sensorimotor Gating in Cocaine-Related Disorder with Comorbid Schizophrenia or Antisocial Personality Disorder Sensorimotor gating is impaired in male patients with bipolar disorder and depression.